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Omeprazole
[2-Chloro-3-trifluoromethylpyridine] [2-Cyclohexenone] [3-Bromo-5-Methoxybenzyl Alcohol] [3-Bromo-5-Methoxytoluene] [3-Bromobenzenesulfonyl Chloride] [3-Bromo-2-trifluoromethylpyridine] [3-Methoxybenzenesulfonyl Chloride] [3,5-Dibromoanisole] [Indole Series] [5-Chloro-2-picoline] [Featured Items] [Acyclovir] [Clopidogrel] [ethyl 3-oxocyclohexanecarboxylate] [Lansoprazole] [Meropenem] [Omeprazole] [Pantoprazole Sodium] [Pyridine Series] [Valsartan]
Omeprazole
Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia,
peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and
Zollinger-Ellison syndrome. Omeprazole is one of the most widely
prescribed drugs internationally and is available over the counter in some
countries.
Omeprazole is a racemate. It contains a tri-coordinated sulfur atom in a
pyramidal structure and therefore can exist in equal amounts of both the S
and R enantiomers. In the acidic conditions of the stomach, both are
converted to achiral products, which reacts with a cysteine group in H+/K+
ATPase, thereby inhibiting the ability of the parietal cells to produce
gastric acid.
If any enquiry on this product, please feel free
to contact us via
info@asiaron.com
-
Basic information
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Item |
Index |
|
Chemical Name |
Omeprazole;
5-methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]-3H-benzoimidazole;
5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole;
2-(((3,5-Dimethyl-4-methoxy-2-pyridyl)methyl)sulfinyl)-5-methoxy-1H-benzimidazole;
6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole;
5-甲氧基-2-［（4-甲氧基-3，5-二甲基-2-吡啶基）-甲基亚砜］-3H-苯并咪唑 (Chinese);
奥美拉唑 (Chinese) |
|
IUPAC name |
5-methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]-3H-benzoimidazole |
|
InChI |
1/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20) |
|
InChIKey |
|
|
SMILES |
O=S(C1=NC2=C(C=CC(=C2)OC)N1)CC3=C(C(=C(C=N3)C)OC)C |
|
Molecular Formula |
C17H19N3O3S |
|
CAS No. |
73590-58-6 |
|
Chemical Structure |
 |
|
Molecular
Weight |
345.42 |
|
Appearance |
White powder |
|
Assay
(C17H19N3O3S; Dried Basis) |
98.0-102.0% : 98.0%-102.0% (USP); 99.0%-101.0% (BP/EP) |
|
Completeness of Solution |
To
pass test |
|
Color of Solution |
To
pass test |
|
Chromatographic Purity |
To
pass test |
|
Loss on Drying |
0.5%
max.
: 0.2% max. (BP/EP)；0.5% max. (USP) |
|
Residue on Ignition |
0.1%
max. |
|
Heavy Metals |
0.002% max. |
|
Organic Volatile Impurities |
To
pass test |
-
Specification
USP24/BP2002/EP4
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Hazard
Class
Not regulated
Most important hazards: Xi - Irritant
-
Storage
Moisture sensitive, store in cool, dry
and ventilated place in tightly sealed containers, protected from
heat and sunlight.
Shelf life: 12 months or longer if stored properly
- Packing
In
5kg/25kg
drum
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