Niacin

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Nutrition >>> Niacin

[Betaine HCl] [Betaine Anhydrous] [Betaine Citrate] [Niacin] [Nicotinamide] [Chromium Picolinate] [Chromium Polynicotinate] [D Calcium Pantothenate] [SAM-e]

Niacin / Nicotinic Acid
(Vitamin B3 / Vitamin PP)

Niacin (also called Nicotinic Acid) and Niacinamide (also called Nicotinamide), two compounds of water-soluble vitamin B complex, are active in the metabolism of body. Chemically they are 3-Pyridinecarboxylic acid and 3-Pyridinecarboxamide respectively. Commercially, niacin is obtained from beta -picoline or from quinoline, which are both obtainable from coal tar.

Niacinamide, more water soluble, is the amide form of niacin. When an amide molecule attaches itself to niacin, it becomes niacinamide. The B vitamins niacin and niacinamide are known as preventives of pellagra. Niacin is interchangeable in metabolism with its amide, niacinamide. Nicotinamide is hydrolyzed to the acid in the digestive tract of non-ruminants. After absorption in the mucosa, the amide is formed again. In the rumen of ruminants, nicotinamide is converted in a short time to nicotinic acid.

Nicotinamide and nicotinic acid are therefore equivalent in action in the case of farm animals. These are key ingredients in animal feed and animal feed premixes as these contribute to numerous metabolic reactions as hydrogen transferring coenzymes. Niacin acts to reduce plasma cholesterol, as a vasodilator and to treat pellagra. Niacin is used for the prophylaxis. Their derivatives are used for these effects.

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Basic information

Item

Index

Chemical Name

3-Pyridinecarboxylic acid; Nicotinic acid; Nicotinipca; Pyridine-モ-carboxylic acid; Vitamin B; 3-Carboxylpyridine; 3-Carboxypyridine; anti-Pellagra vitamin; Acidum nicotinicum; Nicotine acid; Pyridine-3-carbonic acid; Pyridine-3-carboxylic acid; Kyselina nikotinova; Nicotinoylhydrazine; Nicotinsaure (German); Pyridine-carboxylique-3; M-pyridinecarboxylic Acid; Acide Nicotinique (French); Pyridine-carboxylique-3 (French); 烟酸(Chinese);

Molecular Formula

C₆H₅NO₂

Chemical Formula

Molecular Weight

123.11

CAS No.

59-67-6

EINECS NO.

200-441-0

Physical Properties

White or yellowish crystal or crystalline powder, odorless or slightly odoriferous, being acid in aqueous solution; Soluble in boiling water or ethanol, slightly soluble in water, sparingly soluble in ether, and easily soluble in carbonate solutions and alkali solutions

Stability

Stable under ordinary conditions

NFPA rating

Health: 1 Flammability: 1 Reactivity: 0

Application

feed additive, pharmaceuticals, food enrichment, animal mixes for livestock

BP2003
In conformity with the standard of BP2003

Item	Index
Appearance	white crystalline powder
Solubility	Complies
Related Substances	Complies
Assay [C6H5NO2]，%	99.0-101.0
Melting Point, ℃	234-240
Chloride, %	0.02 max.
Loss on Drying, %	1.0 max.
Sulphated Ash，％	0.1 max.
Heavy Metals，%	0.002 max.

USP29
In conformity with the standard of US29

	Item	Index
	Appearance	white crystalline powder
	Solubility	Complies
	Ordinary Impurities	Complies
	Organic Volatile Impurities	Complies
	Identification	Complies
	Assay [C6H5NO2]，%	99.0-101.0
	Sulfate, %	0.02 max.
	Chloride, %	0.02 max.
	Loss on Drying, %	0.5 max.
	Heavy Metals，%	0.002 max.
	Residue on Ignition，％	0.1 max.

GB7300-87
In conformity with the standard of GB7300-87

Item	Index
Appearance	white to yellowish crystalline powder
Solubility	Complies
Melting Point, ℃	234-238
Identification	Complies
Assay [C6H5NO2]，%	99.0-101.0
Sulfate, %	0.02 max.
Chloride, %	0.02 max.
Loss on Drying, %	0.5 max.
Heavy Metals，%	0.002 max.
Residue on Ignition，％	0.1 max.

Packing
In 20Kg/Carton or 25Kg/bag or 25Kg/drum net each