Meropenem

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Meropenem

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Basic information

Item	Index
Chemical Name	Meronem ; Meropenem ; 4R,5S,6S)-3-[[(3S,5S)-5-[(D-imethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[ 3 . 2 . 0 ]hept-2-ene-2-carboxylic acid ; 4R,5S,6S)-3-[[(3S,5S)-5-[(D-imethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-me ; 3-[[5-[(二甲氨基)羰基]-3-吡咯烷基]硫代]-6-(1-羟乙基)-4-甲基-7-氧代-1-氮杂双环[3,2,0]庚-2-烯-2-羧酸(Chinese) ; 美罗培南(Chinese)
IUPAC name
InChI
InChIKey
SMILES
Molecular Formula	C₁₇H₂₅N₃O₅S
CAS No.	96036-03-2
Chemical Structure
Molecular Weight	383.46
Appearance	white or light yellow crystal powder, odorless and bitter
Specific rotation	-17^o ～ -21^o
PH value	4.0～6.0
Loss on Drying	1.0% max.
Residue on Ignition	0.2% max.
Assay	98％min.
Organic Impurities	Single impurities - 0.5% max. Total impurities - 1.5% max.
Dichloromethane and Acetone	Dichloromethane - 0.06% max. Acetone - 0.5% max.
Moisture	11.4%～13.4%
Heavy metal	20ppm max.
Solubility	本品在甲醇中溶解，在水中略溶，在丙酮、乙醇或乙醚中不溶；在0.1mol/L氢氧化钠溶液中溶解，在0.1mol/L盐酸溶液中略溶

Hazard Class
UN 2929
Most important hazards: T - Toxic
　
Storage
store in cool, dry and ventilated place in tightly sealed containers, protected from heat and sunlight.
Shelf life: 12 months or longer if stored properly
　
Packing
In 5kg/25kg drum