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Lansoprazole


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Custom Synthesis >>> Lansoprazole

[2-Chloro-3-trifluoromethylpyridine] [2-Cyclohexenone] [3-Bromo-5-Methoxybenzyl Alcohol] [3-Bromo-5-Methoxytoluene] [3-Bromobenzenesulfonyl Chloride] [3-Bromo-2-trifluoromethylpyridine] [3-Methoxybenzenesulfonyl Chloride] [3,5-Dibromoanisole] [Indole Series] [5-Chloro-2-picoline] [Featured Items] [Acyclovir] [Clopidogrel] [ethyl 3-oxocyclohexanecarboxylate] [Lansoprazole] [Meropenem] [Omeprazole] [Pantoprazole Sodium] [Pyridine Series] [Valsartan]


Lansoprazole
Lansoprazole is a proton pump inhibitor which prevents the stomach from producing acid. It was first approved by the FDA in 1995.

Lansoprazole is a proton pump inhibitor (PPI) in the same pharmacologic class as omeprazole. Lansoprazole has been marketed for many years and is one of several PPI's available. Lansoprazole's plasma elimination half-life is not proportional to the duration of the drug's effects (i.e. gastric acid suppression). The mean plasma elimination half-life is 1.5 hours, and the effects of the drug last for over 24 hours after it has been used for 1 day or more.


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  • Basic information

    Item

    Index

    Chemical Name

    2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole; (+-)-lansoprazole; Lansoprazole; 2-[[[3-甲基-4-(2,2,2-三氟乙氧基)-2-吡啶基]甲基]-亚磺酰基]-1H-苯并咪唑 (Chinese); 兰索拉唑 (Chinese)

    IUPAC name

    2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]-1H-benzoimidazole

    InChI

     

    InChIKey

     
    SMILES  

    Molecular Formula

    C16H14F3N3O2S

    CAS No.

    103577-45-3

    Chemical Structure

    Molecular Weight

    369.36

    Appearance

    white crystal powder, odorless

    Melting point

    170.0-170.5℃
    Related substance complied
    Loss on Drying 1.0% max.
    Residue on Ignition  0.1% max.
    Assay (HPLC) 99.5%min.
    Organic Impurities complied
  • Specification
    USP24/BP2002/EP4
     

  • Hazard Class
    Not regulated
    Most important hazards: Xi - Irritant
     

  • Storage
    Moisture sensitive, store in cool, dry  and ventilated place in tightly sealed containers, protected from heat and sunlight.
    Shelf life: 12 months or longer if stored properly

     

  • Packing
    In
    5kg/25kg drum

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Last update
: 2010/10/07