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Nutrition >>>
Niacinamide
[Betaine HCl] [Betaine Anhydrous] [Betaine Citrate] [Niacin] [Nicotinamide] [Chromium Picolinate] [Chromium Polynicotinate] [D Calcium Pantothenate] [SAM-e]
Niacinamide / Nicotinamide
(Vitamin B3 / Vitamin PP)
Nicotinamide,
also known as niacinamide and nicotinic acid amide, is the amide of
nicotinic acid (vitamin B3). Nicotinamide is a water-soluble vitamin and is
part of the vitamin B group.
Nicotinamide has demonstrated anti-inflammatory actions which may be of
benefit in patients with inflammatory skin conditions. These conditions
include acne vulgaris, and the compound can suppress antigen induced-lymphocytic
transformation and inhibit of 3'-5' cyclic AMP phosphodiesterase.
Nicotinamide has demonstrated the ability to block the inflammatory actions
of iodides known to precipitate or exacerbate inflammatory acne.
Animal studies show that nicotinamide has anti-anxiety (anxiolytic)
properties. It may work in a way similar to benzodiazepines.
Nicomide (take note the naming similarity), is an acne medication, and in
its vitamin supplement form, the most predominant ingredient is 750 mg of
nicotinamide, based on this area of research.
Nicotinamide lacks the vasodilator, gastrointestinal, hepatic, and
hypolipemic actions of nicotinic acid. As such nicotinamide has not been
shown to produce the flushing, itching and burning sensations of the skin as
is commonly seen when large doses of nicotinic acid are administered orally.
However, nicotinamide can produce liver toxicity at high doses.[6] In
overall, it rarely causes side effects, and is considered generally safe as
a food additive, component in cosmetics and medication.[7]
Nicotinamide is produced by the aqueous ammonolysis of 3-cyanopyridine (nicotinonitrile)
and subsequent crystallisation.
If any enquiry for
this product, please contact us via mail:
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- Basic information
|
Item |
Index |
|
Chemical Name |
3-Pyridinecarboxamide; Nicotinamide; Propamine A; モ-Pyridinecarboxamide;
Nicosylamide; Nicotamide; Nicotilamide; Nicotine acid amide;
Nicotinic acid amide; Nicotinic amide; Nicotylamide; Nicovit;
Nicovitina; Nikotinamid; Niocinamide; 3-carbamoyl-Pyridine; Vitamin
B; Vitamin B3; 3-Carbamoylpyridine; 3-Pyridinecarboxylic acid amide;
Picolinamide; Niamide; Nicamide; Nicogen; Nicomidol; Nicota;
Nicotililamido; Nicotinsaureamid; Nicotol; Nicovel; Nicovitol;
Nicozymin; Vitamin PP; Witamina PP; Amid kyseliny nikotinove;
Amnicotin; Norcholine; Amid Kyseliny Nikotinove (Czech); M-(Aminocarbonyl)Pyridine;
Delonin Amide; Nicotinsaureamid (German); Nikotinsaeureamid
(German); 烟酸(Chinese); |
|
Molecular Formula |
C6H6N2O |
|
Chemical
Structure |
|
|
Molecular
Weight |
122.13 |
|
CAS No.
|
98-92-0 |
|
EINECS NO.
|
202-713-4 |
|
Physical Properties |
White or yellowish crystal or crystalline powder, odorless or
slightly odoriferous, bitter taste, easily soluble in water or
ethanol and soluble in glycerol |
|
Stability |
Stable under ordinary conditions |
|
NFPA rating |
Health: 1 Flammability: 1 Reactivity: 0 |
|
Application |
feed additive, pharmaceuticals, food enrichment, animal mixes for
livestock |
- USP29
In conformity with the standard of USP29
|
Item |
Index |
|
Appearance |
white crystalline powder |
|
Solubility
|
Complies |
|
Readily
Carbonizable Substances |
Complies |
|
Identification
|
Complies |
|
Organic
Volatile Impurities |
Complies |
|
Assay
[C6H6N2O]，% |
98.5-101.5 |
|
Melting Point, ℃
|
128-131 |
|
Loss on Drying, %
|
0.5 max. |
|
Heavy Metals，%
|
0.003 max. |
|
Residue on Ignition，％ |
0.1 max. |
- BP2003
In conformity with the standard of BP2003
|
Item |
Index |
|
Appearance |
white crystalline powder |
|
Solubility
|
Complies |
|
Related
Substances |
Complies |
|
Identification
|
Complies |
|
Assay
[C6H6N2O]，% |
99.0-101.0 |
|
Melting Point, ℃
|
128-131 |
|
PH
|
6.0-7.5 |
|
Loss on Drying, %
|
0.5 max. |
|
Heavy Metals，%
|
0.003 max. |
|
Sulphated Ash，％ |
0.1 max. |
- GB7301-87
In conformity with the standard of GB7301-87
|
Item |
Index |
|
Appearance |
white crystalline powder |
|
Solubility
|
Complies |
|
Identification
|
Complies |
|
Assay
[C6H6N2O]，% |
98.5-101.0 |
|
Melting Point, ℃
|
128-131 |
|
PH
|
5.5-7.5 |
|
Loss on Drying, %
|
0.5 max. |
|
Heavy Metals，%
|
0.002 max. |
|
Residue on Ignition，％ |
0.1 max. |
- Packing
In 25Kg/drum or 20Kg/carton net each
- Dosage
15-30mg /kg in swine,30-60mg /kg in broilers, 30-40mg /kg in calves (milk
replacer), 60-80mg /kg in turkeys, 50-80mg /kg in fish.
- Period of validity
2years
|
